Ctp biosynthetic process
WebCTP biosynthetic process Source:UniProtKB. 1 publication. Biological Process: glutamine metabolic process Source:UniProtKB-KW. Biological Process: nucleobase-containing compound metabolic process Source:ProtInc. 1 publication. Biological Process: pyrimidine nucleobase biosynthetic process Source:GO_Central. CTP (cytidine triphosphate) synthetase catalyzes the last committed step in pyrimidine nucleotide biosynthesis: ATP + UTP + glutamine → ADP + Pi + CTP + glutamate It is the rate-limiting enzyme for the synthesis of cytosine nucleotides from both the de novo and uridine salvage pathways. The reaction proceeds by the … See more CTP synthase is an enzyme (EC 6.3.4.2) involved in pyrimidine biosynthesis that interconverts UTP and CTP. See more Active CTP synthase exists as a homotetrameric enzyme. At low enzyme concentrations and in the absence of ATP and UTP, CTP synthase exists as inactive monomer. As enzyme concentration increases, it polymerizes first to a dimer (such as the form … See more CTP synthase has been reported to form filaments in several different organisms. These include bacteria (C. crescentus), yeast ( See more • Pyrimidine biosynthesis See more Two isozymes with CTP synthase activity exist in humans, encoded by the following genes: • See more CTP synthase is precisely regulated by the intracellular concentrations of CTP and UTP, and both hCTPS1 and hCTPS2 have been seen to be maximally active at physiological concentrations of ATP, GTP, and glutamine. The activity of … See more Upregulated CTP synthase activity has been widely seen in human and rodent tumors. Mutations in the … See more
Ctp biosynthetic process
Did you know?
WebCTP synthase 1: RGD ID: 1311060: Description: Predicted to enable CTP synthase activity and identical protein binding activity. Predicted to be involved in lymphocyte proliferation and pyrimidine-containing compound biosynthetic process. Predicted to be active in cytoophidium and cytoplasm. Human ortholog(s) of this gene implicated in ... WebJul 25, 2006 · Biological Process: CTP biosynthetic process Source:UniProtKB. Biological Process: glutamine metabolic process Source:UniProtKB-KW. Biological Process: pyrimidine nucleobase biosynthetic process Source:GO_Central. 1 publication. Biological Process: T cell proliferation Source:UniProtKB. Expand table. Complete GO annotation …
WebBiological Process Description The chemical reactions and pathways resulting in the formation of cytidine 5'-triphosphate (CTP) from simpler components. Synonyms … WebFeb 15, 2024 · Gene Summary. CTP synthase ( Ctps) encodes the rate limiting enzyme for the de novo synthesis of the nucleotide CTP. It forms an evolutionarily conserved filamentous structure termed the cytoophidium. It acts downstream of the product of Myc and is required for Myc -mediated cell size control. [Date last reviewed: 2024-03-07] ( …
WebCtps2. Name: CTP synthase 2. RGD ID: 1563369. Description: Predicted to enable CTP synthase activity and identical protein binding activity. Predicted to be involved in CTP … WebGene Ontology Term: GTP biosynthetic process. GO ID. GO:0006183. Aspect. Biological Process. Description. The chemical reactions and pathways resulting in the formation of GTP, guanosine triphosphate.
WebPredicted to enable CTP synthase activity and identical protein binding activity. Predicted to be involved in CTP biosynthetic process and pyrimidine nucleobase biosynthetic process. Predicted to be active in cytoophidium and cytoplasm. Is expressed in germ line and intestine. Human ortholog (s) of this gene implicated in immunodeficiency 24.
http://amigo.geneontology.org/amigo/term/GO:0006241 photo converter in 20 kbWebFunction. Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ( PubMed: 5793714 ). Required for repair of UV radiation- and etoposide-induced DNA damage ( PubMed: 18983998 ). how does convectional rainfall workWebDec 13, 2024 · Enables CTP synthase activity. Involved in CTP biosynthetic process and larval lymph gland hemopoiesis. Acts upstream of with a positive effect on phospholipid metabolic process. Located in cytoophidium and cytoplasm. Is expressed in several structures, including extended germ band embryo; germ layer; ovary; presumptive … how does cooking help a child\u0027s developmentWebDescription: Homo sapiens CTP synthase 2 (CTPS2), transcript variant 3, mRNA. (from RefSeq NM_001144002) RefSeq Summary (NM_001144002): The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of … how does convection roast workWebOther organisms process uric acid further prior to excretion 1) Adenosine deaminase converts adenosine to inosine 2) Inosine is hydrolyzed to its free base, hypoxanthine, by the action of purine nucleoside phosphorylase. ... ATCase is feedback inhibited by CTP, the final product of this biosynthetic pathway how does conversations with friends endWebPyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2. UniRule annotation. Features. Showing features for binding site, active site. Type. ID ... Biological Process 'de novo' CTP biosynthetic process Source:UniProtKB-UniPathway. Biological Process: glutamine metabolic process Source:UniProtKB-KW. Expand table. how does cookie monster eat a cookieWebAnnotations Gene Ontology Term: CTP biosynthetic process GO ID GO:0006241 Aspect Biological Process Description The chemical reactions and pathways resulting in the … how does cooking support maths development